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Home > FC Antibody

Anti-Human CD40 Monoclonal Antibody(FITC Conjugated)

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Product name: Anti-Human CD40 Monoclonal Antibody(FITC Conjugated)
Catalog:

DL20558F

Synonyms : Tumor necrosis factor receptor superfamily member 5,Cd40,B-cell surface antigen CD40,Bp50,CD40L receptor,CD40,Tnfrsf5
Reactivity: Human
Applications: FCM
Size: 20 Tests/50 Tests/100 Tests/200 Tests
Host: Mouse
Clonality:
Conjugation:
Background:

CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand). The 5C3 antibody has been reported to promote B cell proliferation in the presence of anti-IgM, IL-4 or PMA, partially blocking CD40 binding to CD40L, and B cells rescue from apoptosis.

Concentration:
Buffer: PBS with 0.05% Proclin300, 1% BSA
Gene_ID: 958
Clone_NO: 3A8
SwissProt: P25942
Isotype: Mouse IgG2a, ?
Storage: Store at 2~8℃. Do not freeze.

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