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FAQ
Anti-Human CD16 Monoclonal Antibody(Biotin Conjugated)
| Product name: | Anti-Human CD16 Monoclonal Antibody(Biotin Conjugated) | |
| Catalog: | DL20201F |
|
| Synonyms : | Low affinity immunoglobulin gamma Fc region receptor III-A,FCGR3A,CD16a antigen,Fc-gamma RIII-alpha,Fc-gamma RIII,Fc-gamma RIIIa,FcRIII,FcRIIIa,FcR-10,IgG Fc receptor III-2,CD16a | |
| Reactivity: | Human | |
| Applications: | FCM | |
| Size: | 25 ug/100 ug | |
| Host: | Mouse | |
| Clonality: | ||
| Conjugation: | ||
| Background: | CD16 is known as low affinity IgG receptor III (Fc??RIII). It is expressed as two distinct forms (CD16a and CD16b). CD16a (Fc??RIIIA) is a 50-65 kD polypeptide-anchored transmembrane protein. It is expressed on the surface of NK cells, activated monocytes, macrophages, and placental trophoblasts in humans. CD16b (Fc??RIIIB) is a 48 kD glycosylphosphatidylinositol (GPI)-anchored protein. Its extracellular domain is over 95% homologous to that of CD16a, and it is expressed specifically on neutrophils. CD16 binds aggregated IgG or IgG-antigen complex which functions in NK cell activation, phagocytosis, and antibody-dependent cell-mediated cytotoxicity (ADCC). |
|
| Concentration: | 0.5 mg/mL | |
| Buffer: | PBS with 0.05% Proclin300, 1% BSA | |
| Gene_ID: | 2214 | |
| Clone_NO: | CB16 | |
| SwissProt: | P08637 | |
| Isotype: | Mouse IgG1, ? | |
| Storage: | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. | |
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