AF/LE Purified Anti-Mouse CD54 Monoclonal Antibody

Product name:	AF/LE Purified Anti-Mouse CD54 Monoclonal Antibody
Catalog:	DL20339F
Synonyms :	Intercellular adhesion molecule 1,Icam1,MALA-2,MyD10,CD54,Icam-1
Reactivity:	Mouse
Applications:	FCM,IF
Size:	50 ug/500 ug/1 mg/
Host:	Rat
Clonality:
Conjugation:
Background:	CD54 is a 90 kD immunoglobulin superfamily member also known as ICAM-1 and Ly-47. It is expressed on activated endothelial cells, high endothelial venules (HEV), T and B cells, monocytes/ macrophages, granulocytes, and dendritic cells. CD54 is an important intracellular adhesion molecule that participates in T cell-T cell, T cell-B cell, and T cell-target cell interactions via binding of LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). CD54 has also been shown to be involved in lymphocyte trafficking, making it an important molecule in many immune reactions and inflammation. CD54 is also a receptor for rhinovirus. The YN1/1.7.4 antibody has been reported to block binding of mouse CD54 to LFA-1 and Mac-1, inhibit cell-cell adhesion, and function in antigen presentation to T cells and leukocyte migration to inflammatory tissues.
Concentration:	0.2 mg/mL
Buffer:	0.2 um filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg ( < 0.002EU/ug) as Determined by LAL gel clotting assay.
Gene_ID:	15894
Clone_NO:	YN1/1.7.4
SwissProt:	P13597
Isotype:	Rat IgG2b, ?
Storage:	Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.

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DL20339F