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FAQ
AF/LE Purified Anti-Mouse CD8a Monoclonal Antibody
| Product name: | AF/LE Purified Anti-Mouse CD8a Monoclonal Antibody | |
| Catalog: | DL21247F |
|
| Synonyms : | T-cell surface glycoprotein CD8 alpha chain,CD8A,T-lymphocyte differentiation antigen T8/Leu-2,MAL | |
| Reactivity: | Mouse | |
| Applications: | Block, Depletion, FCM, WB, IF, IP | |
| Size: | 50 ug/500 ug/1 mg/ | |
| Host: | Rat | |
| Clonality: | ||
| Conjugation: | ||
| Background: | CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked ?? and ?? chains that form the ??(CD8a)/??(CD8b) heterodimer and ??/?? homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 ??/?? heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR ??/?? T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 ??/?? homodimer is expressed on a subset of ??/?? TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck. |
|
| Concentration: | 0.2 mg/mL | |
| Buffer: | 0.2 um filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg ( < 0.002EU/ug) as Determined by LAL gel clotting assay. | |
| Gene_ID: | 12525 | |
| Clone_NO: | 53-6.7 | |
| SwissProt: | P01731 | |
| Isotype: | Rat IgG2a, ? | |
| Storage: | Store at 2~8℃. Do not freeze. | |
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