AF/LE Purified Anti-Mouse CD274/PD-L1 Monoclonal Antibody

Product name:	AF/LE Purified Anti-Mouse CD274/PD-L1 Monoclonal Antibody
Catalog:	DL21654F
Synonyms :	B7-H1, PD-L1,Programmed cell death ligand 1,B7 homolog 1,B7-H, B7H1, PDL1, PDCD1L1, PDCD1LG1
Reactivity:	Mouse
Applications:	FCM,IHC,IF,Block
Size:	50 ug/500 ug/1 mg/
Host:	Rat
Clonality:
Conjugation:
Background:	CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-?? activated endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have shown that B7-H1 is able to costimulate T cell growth and cytokine production. CD274 is involved in costimulation essential for T cell proliferation and production of IL-10 and IFN-??, in an IL-2-dependent and a PD-1-independent manner. Its interaction with PD-1 inhibits T cell proliferation and cytokine production.
Concentration:	0.2 mg/mL
Buffer:	0.2 um filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg ( < 0.002EU/ug) as Determined by LAL gel clotting assay.
Gene_ID:	60533
Clone_NO:	10F.9G2
SwissProt:	Q9EP73
Isotype:	Rat IgG2b, ?
Storage:	Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.

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DL21654F