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FAQ
Anti-Human IL-21 Monoclonal Antibody(PE Conjugated)
| Product name: | Anti-Human IL-21 Monoclonal Antibody(PE Conjugated) | |
| Catalog: | DL22176F |
|
| Synonyms : | Interleukin-21,IL-21,Za11 | |
| Reactivity: | Human | |
| Applications: | ICFCM | |
| Size: | 20 Tests/50 Tests/100 Tests/200 Tests | |
| Host: | Mouse | |
| Clonality: | ||
| Conjugation: | ||
| Background: | Interleukin 21 (IL-21) is a potent immunomodulatory cytokine mainly produced by NKT and CD4+ T-cells, particularly the inflammatory Th17 subset, and has pleiotropic effects on both innate and adaptive immune responses. These actions include positive effects such as enhancing proliferation of NK cells and cytotoxic T cells, and inhibitory effects on the antigen-presenting function of dendritic cells. It can also be proapoptotic for B cells and NK cells. Studies have shown that IL-21 is also an autocrine cytokine that potently induces Th17 differentiation, suppresses Foxp3 expression, and serves as a target for treating inflammatory diseases. |
|
| Concentration: | ||
| Buffer: | PBS with 0.05% Proclin300, 1% BSA | |
| Gene_ID: | 59067 | |
| Clone_NO: | 3A3-N2 | |
| SwissProt: | Q9HBE4 | |
| Isotype: | Mouse IgG1, ? | |
| Storage: | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. | |
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