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Home > FC Antibody

Purified Anti-Human CD45 Monoclonal Antibody

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Product name: Purified Anti-Human CD45 Monoclonal Antibody
Catalog:

DL20580F

Synonyms : Receptor-type tyrosine-protein phosphatase C,Ptprc,L-CA,Ly-5,T200,CD45
Reactivity: Human
Applications: FCM
Size: 25 ug/100 ug
Host: Mouse
Clonality:
Conjugation:
Background:

CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.

Concentration: 0.2 mg/mL
Buffer: PBS with 0.05% Proclin300
Gene_ID: 5788
Clone_NO: 9.4
SwissProt: P08575
Isotype: Mouse IgG2a, ?
Storage: Store at 2~8℃. Do not freeze.

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