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FAQ
Anti-Mouse CD122 Monoclonal Antibody(AF488 Conjugated)
| Product name: | Anti-Mouse CD122 Monoclonal Antibody(AF488 Conjugated) | |
| Catalog: | DL20477F |
|
| Synonyms : | Interleukin-2 receptor subunit beta,Il2rb,IL-2 receptor subunit beta, IL-2R subunit beta,IL-2RB,High affinity IL-2 receptor subunit beta,p70-75,CD122 | |
| Reactivity: | Mouse | |
| Applications: | FCM | |
| Size: | 25 ug/50 ug/100 ug/200 ug | |
| Host: | Rat | |
| Clonality: | ||
| Conjugation: | ||
| Background: | CD122 is a 70-75 kD IL-2 receptor ?? chain also known as IL-2R??, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2R?? chain can combine with either the common ?? subunit (??c, CD132) alone or with the ??c subunit and the IL-2R?? subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The 5H4 antibody does not block IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis. |
|
| Concentration: | 0.5 mg/mL | |
| Buffer: | PBS with 0.05% Proclin300, 1% BSA | |
| Gene_ID: | 16185 | |
| Clone_NO: | 5H4 | |
| SwissProt: | P16297 | |
| Isotype: | Rat IgG2a, ? | |
| Storage: | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. | |
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