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FAQ
AF/LE Purified Anti-Mouse CD120b Monoclonal Antibody
| Product name: | AF/LE Purified Anti-Mouse CD120b Monoclonal Antibody | |
| Catalog: | DL20544F |
|
| Synonyms : | Tumor necrosis factor receptor superfamily member 1B,Tnfrsf1b,Tumor necrosis factor receptor 2,TNF-R2,TNF-RII,TNFR-II,p75,p80 TNF-alpha receptor,CD120b | |
| Reactivity: | Mouse | |
| Applications: | FCM,WB,Block,IP | |
| Size: | 50 ug/500 ug/1 mg/ | |
| Host: | Armenian Hamster | |
| Clonality: | ||
| Conjugation: | ||
| Background: | CD120b is a 75 kD type I transmembrane protein, also known as Tumor Necrosis Factor Receptor Type II (TNFRII) or p75. It is expressed on a variety of cells at low levels; the expression is upregulated upon activation. This receptor binds both TNF-?? and LT-?? (also known as TNF-??). In association with TRAF1 and TRAF2, the receptor crosslinking induced by TNF-?? or LT-?? trimers is critical for signal transduction, leading to apoptosis, NF-kB activation, increased expression of proinflammatory genes, tumor necrosis, and cell differentiation depending on cell type and differentiation state. |
|
| Concentration: | 0.2 mg/mL | |
| Buffer: | 0.2 um filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg ( < 0.002EU/ug) as Determined by LAL gel clotting assay. | |
| Gene_ID: | 21938 | |
| Clone_NO: | TR75-54.7 | |
| SwissProt: | P25119 | |
| Isotype: | Armenian Hamster IgG | |
| Storage: | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. | |
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