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Home > FC Antibody

Anti-Mouse CD103 Monoclonal Antibody(PE/Cyanine5 Conjugated)

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Product name: Anti-Mouse CD103 Monoclonal Antibody(PE/Cyanine5 Conjugated)
Catalog:

DL21013F

Synonyms : Integrin alpha-E,Itgae,Integrin alpha M290,CD103
Reactivity: Mouse
Applications: FCM
Size: 20 Tests/50 Tests/100 Tests/200 Tests
Host: Rat
Clonality:
Conjugation:
Background:

CD103 is a type I transmembrane glycoprotein known as ??E integrin or Integrin ??IEL chain. It belongs to the integrin family and is primarily found on intestinal intraepithelial lymphocytes (IEL). CD103 is also expressed on a subpopulation of lamina propria T cells, epithelial dendritic cells, lamina propria-derived dendritic cells, and a small subset of peripheral lymphocytes. T regulatory cells express high level of CD103. The CD103 expression on lymphocytes can be induced upon activation and TGF-?? stimulation. In association with integrin ??7, CD103 is expressed as ??E/??7 heterodimer. Mature CD103 protein can be cleaved into 2 chains, a 150 kD (C-terminal) chain and a 25 kD (N-terminal) chain, which remain linked by disulfide bonds. CD103 binds to E-cadherin and mediates homing of lymphocytes to the intestinal epithelium.

Concentration:
Buffer: PBS with 0.05% Proclin300, 1% BSA
Gene_ID: 16407
Clone_NO: M290
SwissProt: Q60677
Isotype: Rat IgG2a, ?
Storage: Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.

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