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FAQ
Anti-Mouse CD103 Monoclonal Antibody(AF647 Conjugated)
| Product name: | Anti-Mouse CD103 Monoclonal Antibody(AF647 Conjugated) | |
| Catalog: | DL21018F |
|
| Synonyms : | Integrin alpha-E,Itgae,Integrin alpha M290,CD103 | |
| Reactivity: | Mouse | |
| Applications: | FCM | |
| Size: | 20 Tests/50 Tests/100 Tests/200 Tests | |
| Host: | Rat | |
| Clonality: | ||
| Conjugation: | ||
| Background: | CD103 is a type I transmembrane glycoprotein known as ??E integrin or Integrin ??IEL chain. It belongs to the integrin family and is primarily found on intestinal intraepithelial lymphocytes (IEL). CD103 is also expressed on a subpopulation of lamina propria T cells, epithelial dendritic cells, lamina propria-derived dendritic cells, and a small subset of peripheral lymphocytes. T regulatory cells express high level of CD103. The CD103 expression on lymphocytes can be induced upon activation and TGF-?? stimulation. In association with integrin ??7, CD103 is expressed as ??E/??7 heterodimer. Mature CD103 protein can be cleaved into 2 chains, a 150 kD (C-terminal) chain and a 25 kD (N-terminal) chain, which remain linked by disulfide bonds. CD103 binds to E-cadherin and mediates homing of lymphocytes to the intestinal epithelium. |
|
| Concentration: | ||
| Buffer: | PBS with 0.05% Proclin300, 1% BSA | |
| Gene_ID: | 16407 | |
| Clone_NO: | M290 | |
| SwissProt: | Q60677 | |
| Isotype: | Rat IgG2a, ? | |
| Storage: | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. | |
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