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Home > FC Antibody

Anti-Human TCR γ/δ Monoclonal Antibody(PE/Cyanine5.5 Conjugated)

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Product name: Anti-Human TCR γ/δ Monoclonal Antibody(PE/Cyanine5.5 Conjugated)
Catalog:

DL21773F

Synonyms : T cell receptor ??/??, ??/?? TCR, TCR-??/?
Reactivity: Human
Applications: FCM
Size: 20 Tests/50 Tests/100 Tests/200 Tests
Host: Mouse
Clonality:
Conjugation:
Background:

CD49d is a 150 kD ?? integrin chain known as ??4 integrin or VLA-4 ?? chain. It forms a heterodimer with either integrin ??1 (??4??1, VLA-4) or ??7 (??4??7). CD49d is expressed broadly on T lymphocytes, B lymphocytes, monocytes, thymocytes, eosinophils, basophils, mast cells, NK cells, dendritic cells, and some non-hematopoietic cells, but not on normal red blood cells, platelets or neutrophils. VLA-4 binds to VCAM-1 (CD106) and fibronectin. ??4??7 is the receptor for VCAM-1 and MAdCAM-1. CD49d participates in mononuclear cell trafficking to endothelial sites of inflammation and has roles in cell-cell interactions and cell adhesion to extracellular matrices. CD49d is involved in lymphocyte migration, T cell activation, and hematopoietic stem cell differentiation. CD49d is a marker to isolate pure populations of Treg cells due to its absence on Foxp3+ cells.

Concentration:
Buffer: PBS with 0.05% Proclin300, 1% BSA
Gene_ID: 69,646,965
Clone_NO: B1
SwissProt:
Isotype: Mouse IgG1, ?
Storage: Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.

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