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FAQ
Anti-Human CD161 Monoclonal Antibody(AF488 Conjugated)
| Product name: | Anti-Human CD161 Monoclonal Antibody(AF488 Conjugated) | |
| Catalog: | DL21837F |
|
| Synonyms : | CLEC5B, NKRP1A,NKR-P1A,HNKR-P1a,KLRB1 | |
| Reactivity: | Human | |
| Applications: | FCM | |
| Size: | 20 Tests/50 Tests/100 Tests/200 Tests | |
| Host: | Mouse | |
| Clonality: | ||
| Conjugation: | ||
| Background: | CD161 is a type II transmembrane glycoprotein, also known as NKR-P1A, that is expressed as a 40-44 kD homodimer. It is a member of the C-type lectin superfamily. CD161 is expressed on a majority of NK cells, NKT cells, and subsets of peripheral T cells and CD3+ thymocytes. It has been reported that Th17 cells are a subpopulation of CD4+CD161+CCR6+ cells. While the biological function of CD161 is not clear, it has been suggested to serve either as a stimulatory receptor or to inhibit NK cell-mediated cytotoxicity and cytokine production. LLT-1 (lectin-like transcript-1, also named as osteoclast inhibitory lectin or CLEC2D) is the ligand of CD161. |
|
| Concentration: | ||
| Buffer: | PBS with 0.05% Proclin300, 1% BSA | |
| Gene_ID: | 3820 | |
| Clone_NO: | HP-3G10 | |
| SwissProt: | Q12918 | |
| Isotype: | Mouse IgG1, ? | |
| Storage: | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. | |
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