3 times QC before
delivery.
12-month shelf life.
Strong technical
support
Prompt response
After-sales service guarantee.
| > Cytokine |
| >Signal transduction |
| > Enzyme & Kinase |
| > Metabolic pathway |
| > Tumor immunity |
| > Infection immunity |
| > CD& Adhesion molecule |
| > Neuro science |
| > Developmental science |
FAQ
AF/LE Purified Anti-Human CD279/PD-1 Antibody
| Product name: | AF/LE Purified Anti-Human CD279/PD-1 Antibody | |
| Catalog: | DL21621F |
|
| Synonyms : | PD-1, Programmed Death-1 | |
| Reactivity: | Human | |
| Applications: | Block,Neut,FCM | |
| Size: | 50μg | |
| Host: | Mouse | |
| Clonality: | ||
| Conjugation: | ||
| Background: | Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 (B7-H1) and PD-L2 (B7-DC) are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion. |
|
| Concentration: | 0.5 mg/mL | |
| Buffer: | 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay. | |
| Gene_ID: | 5133 | |
| Clone_NO: | ||
| SwissProt: | Q15116 | |
| Isotype: | Mouse IgG1, κ | |
| Storage: | Store at 2~8°C. Do not freeze. | |
Order or get a Quote
We will reply you within 24 hours!
