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FAQ
FITC Anti-Mouse CD150 Antibody
| Product name: | FITC Anti-Mouse CD150 Antibody | |
| Catalog: | DL22627F |
|
| Synonyms : | Slam,Slamf1,CD 150,Signaling lymphocytic activation molecule | |
| Reactivity: | Mouse | |
| Applications: | FCM | |
| Size: | 50Tests | |
| Host: | Rat | |
| Clonality: | ||
| Conjugation: | ||
| Background: | CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signaling lymphocyte activation molecule) or IPO-3. CD150, a single chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained on Th1 but not Th2 clones. T regulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-γ production by Th1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoietic stem cell studies. |
|
| Concentration: | ||
| Buffer: | PBS with 0.05% Proclin300, 1% BSA | |
| Gene_ID: | 27218 | |
| Clone_NO: | ||
| SwissProt: | Q9QUM4 | |
| Isotype: | Rat IgG2a, λ | |
| Storage: | Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. | |
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