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Home > FC Antibody

PE/Cyanine5 Anti-Human CD326 Antibody

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Product name: PE/Cyanine5 Anti-Human CD326 Antibody
Catalog:

DL23012F

Synonyms : EpCAM,Ep-CAM,GA733-2,M1S2,M4S1,MIC18,TACSTD1, TROP1
Reactivity: Human
Applications: FCM
Size: 20Tests
Host: Mouse
Clonality:
Conjugation:
Background:

CD326 is also known as Ep-CAM, tumor associated calcium signal transducer 1, epithelial cell surface antigen, epithelial glycoprotein 2, EGP2, adenocarcinoma associated antigen, and TROP1. CD326 is a type I transmembrane protein containing six disulfide bridges and one THYRO domain. This cell surface glycosylated 40 kD protein is highly expressed in bone marrow, colon, lung, and most normal epithelial cells and is expressed on carcinomas of gastrointestinal origin. Recently, it has been reported that CD326 expression occurs during the early steps of erythrogenesis. CD326 functions as a homotypic calcium-independent cell adhesion molecule and is believed to be involved in carcinogenesis by its ability to induce genes involved in cellular metabolism and proliferation. CD326 antigen is an immunotherapeutic target for the treatment of human carcinomas.

Concentration:
Buffer: PBS with 0.05% Proclin300, 1% BSA
Gene_ID: 4072
Clone_NO:
SwissProt: P16422
Isotype: Mouse IgG2b, κ
Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

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