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FAQ
PerCP/Cyanine5.5 Anti-Human CD61 Antibody
| Product name: | PerCP/Cyanine5.5 Anti-Human CD61 Antibody | |
| Catalog: | DL23025F |
|
| Synonyms : | GP3A,GPIIIa,ITGB3,Integrin beta-3 | |
| Reactivity: | Human | |
| Applications: | FCM | |
| Size: | 20Tests | |
| Host: | Mouse | |
| Clonality: | ||
| Conjugation: | ||
| Background: | CD61, also known as integrin β3 and glycoprotein IIIa (gpIIIa), is a 90 kD type I integral transmembrane glycoprotein. It is a member of the integrin family, associating with platelet gpIIb (CD41) to form CD41/CD61 complex and with integrin αV (CD51) to form αV/β3 (CD51/CD61) integrin. CD41/CD61 is expressed on platelets and megakaryocytes, and plays a role in platelet activation and aggregation through interaction with fibrinogen, fibronectin, vWF, and other RGD-containing adhesion molecules. CD51/CD61 is expressed on platelets, osteoclasts, fibroblasts, macrophages, and some tumor cells involved in tumor metastasis, and in adenovirus infection through binding to RGD motif in extracellular matrix proteins. |
|
| Concentration: | ||
| Buffer: | PBS with 0.05% Proclin300, 1% BSA | |
| Gene_ID: | 3690 | |
| Clone_NO: | ||
| SwissProt: | P05106 | |
| Isotype: | Mouse IgG1, κ | |
| Storage: | Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. | |
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