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FAQ
PE/TR Anti-Human CD22 Antibody
| Product name: | PE/TR Anti-Human CD22 Antibody | |
| Catalog: | DL23057F |
|
| Synonyms : | B-cell receptor CD22,Cd22,B-lymphocyte cell adhesion molecule,BL-CAM,Sialic acid-binding Ig-like lectin 2,Siglec-2,T-cell surface antigen Leu-14,CD22,Lyb-8, Siglec2 | |
| Reactivity: | Human | |
| Applications: | FCM | |
| Size: | 20Tests | |
| Host: | Mouse | |
| Clonality: | ||
| Conjugation: | ||
| Background: | CD22 is a 130 kD type I transmembrane glycoprotein also known as Siglec-2 and BL-CAM. It is a member of the immunoglobulin superfamily (sialoadhesion subgroup). CD22 is expressed in the cytoplasm of pro-B and pre-B cells, and on the surface of mature B and activated B cells, but not on plasma cells. CD22 is present in the B cell receptor complex and associates with SHP-1, Syk, Lck, Lyn, and phospholipase Cγ1. A primary function of CD22 is thought to be in limiting antigen receptor signaling by modulating B cell activation threshold. CD22 has been shown to bind to CD45RO and CD75, although the natural ligands for this molecule remain controversial. |
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| Concentration: | ||
| Buffer: | PBS with 0.05% Proclin300, 1% BSA | |
| Gene_ID: | 933 | |
| Clone_NO: | ||
| SwissProt: | P20273 | |
| Isotype: | Mouse IgG1, κ | |
| Storage: | Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. | |
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