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Home > FC Antibody

PE/TR Anti-Human CD107a/LAMP-1 Antibody

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Product name: PE/TR Anti-Human CD107a/LAMP-1 Antibody
Catalog:

DL23089F

Synonyms : Lysosome-Associated Membrane Protein 1, LGP-120, LAMP-1
Reactivity: Human
Applications: FCM
Size: 20Tests
Host: Mouse
Clonality:
Conjugation:
Background:

CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a 110-140 kD type I membrane glycoprotein. Mature CD107a is heavily glycosylated from a 40 kD core protein. This molecule is located on the luminal side of lysosomes. Upon activation, CD107a is transferred to the cell membrane surface of activated platelets, activated lymphocytes, macrophages, epithelial cells, endothelial cells, and some tumor cells. CD107a has been suggested to play a role in the protection of lysosomal membrane from lysosomal hydrolases which is involved in cell adhesion and regulation of tumor metastasis, and mediates autoimmune disease progression. CD107a is a ligand for galaptin and E-selectin. Surface expression of LAMP-1 has been shown to correlate with CD8+ T cell and NK cell cytotoxicity.

Concentration:
Buffer: PBS with 0.05% Proclin300, 1% BSA
Gene_ID: 3916
Clone_NO:
SwissProt: P11279
Isotype: Mouse IgG1, κ
Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

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