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Home > FC Antibody

Anti-Mouse IL-17A Monoclonal Antibody(FITC Conjugated)

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Product name: Anti-Mouse IL-17A Monoclonal Antibody(FITC Conjugated)
Catalog:

DL22159F

Synonyms : Interleukin-17A,IL-17,IL-17A,Cytotoxic T-lymphocyte-associated antigen 8,CTLA-8,CTLA8
Reactivity: Mouse
Applications: ICFCM
Size: 20 Tests/50 Tests/100 Tests/200 Tests
Host: Rat
Clonality:
Conjugation:
Background:

IL-17, also known as CTLA-8, is a T cell-expressed pleiotropic cytokine that exhibits a high degree of homology to a protein encoded by the ORF13 gene of herpes virus Saimiri. IL-17 is produced by Th cells (Th17) that are distinct from the traditional Th1- and Th2-cell subsets. IL-23 plays an important role in triggering IL-17 production. Both recombinant and natural IL-17 have been shown to exist as disulfide linked homodimers. IL-17 exhibits multiple biological activities on a variety of cells including: the induction of IL-6 and IL-8 production in fibroblasts, activation of NF-??B, and costimulation of T cell proliferation. IL-17 is an essential inflammatory mediator in the development of autoimmune diseases. Neutralization of IL-17 with monoclonal antibody is able to ameliorate the disease course.

Concentration:
Buffer: PBS with 0.05% Proclin300, 1% BSA
Gene_ID: 16171
Clone_NO: TC11-18H10.1
SwissProt: Q62386
Isotype: Rat IgG1, ?
Storage: Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.

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