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FAQ
Purified Anti-Mouse CD86 Monoclonal Antibody
| Product name: | Purified Anti-Mouse CD86 Monoclonal Antibody | |
| Catalog: | DL20100F |
|
| Synonyms : | T-lymphocyte activation antigen CD86,Cd86,Activation B7-2 antigen,Early T-cell costimulatory molecule 1,ETC-1 | |
| Reactivity: | Mouse | |
| Applications: | FCM,IHC,IF,IP | |
| Size: | 50 ug/100 ug | |
| Host: | Rat | |
| Clonality: | ||
| Conjugation: | ||
| Background: | CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells. |
|
| Concentration: | 0.2 mg/mL | |
| Buffer: | PBS with 0.05% Proclin300 | |
| Gene_ID: | 12524 | |
| Clone_NO: | GL-1 | |
| SwissProt: | P42082 | |
| Isotype: | Rat IgG2a, ? | |
| Storage: | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. | |
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