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Home > FC Antibody

Purified Anti-Human CD45RO Monoclonal Antibody

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Product name: Purified Anti-Human CD45RO Monoclonal Antibody
Catalog:

DL21717F

Synonyms :
Reactivity: Human
Applications: FCM
Size: 25 ug/100 ug
Host: Mouse
Clonality:
Conjugation:
Background:

CD45RO is a 180 kD single chain membrane glycoprotein. It is a splice variant of tyrosine phosphatase CD45, lacking the A, B, and C determinants. The CD45RO isoform is expressed on activated and memory T cells, some B cell subsets, activated monocytes/macrophages, and granulocytes. CD45RO enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1 and CD22. CD45 isoform expression can change in response to cytokines.

Concentration: 0.2 mg/mL
Buffer: PBS with 0.05% Proclin300
Gene_ID: 5788
Clone_NO: UCHL1
SwissProt: P08575
Isotype: Mouse IgG2a, ?
Storage: Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.

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