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Home > FC Antibody

Anti-Human CD45 Monoclonal Antibody(PE/Cyanine5.5 Conjugated)

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Product name: Anti-Human CD45 Monoclonal Antibody(PE/Cyanine5.5 Conjugated)
Catalog:

DL21703F

Synonyms : Receptor-type tyrosine-protein phosphatase C,Ptprc,L-CA,Ly-5,T200,CD45
Reactivity: Human
Applications: FCM
Size: 20 Tests/50 Tests/100 Tests/200 Tests
Host: Mouse
Clonality:
Conjugation:
Background:

CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.

Concentration:
Buffer: PBS with 0.05% Proclin300, 1% BSA
Gene_ID: 5788
Clone_NO: HI30
SwissProt: P08575
Isotype: Mouse IgG1, ?
Storage: Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.

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